Senior Biochemist

Senior Biochemist / Assay Development Scientist, PhoreMost

Role Description: 

PhoreMost® is looking for a talented and innovative senior scientist to join our drug discovery team and support our revolutionary discovery campaigns. The successful candidate will play a key role in building biochemical assays towards novel targets identified from our target discovery SITESEEKER® platform and support the development of small molecules to advance our drug discovery projects. This is a full-time laboratory-based position within a dynamic and multi-disciplinary organisation. 

About us: 

We are a biotech company located in Cambridge, UK. We have developed a next-generation high-throughput screening platform called SITESEEKER® to identify the best new targets for future therapy and the mechanisms to drug them. Our SITESEEKER® platform uses a cutting-edge approach called PROTEINi® (protein interference) to identify novel targets. This technology has the ability to identify hidden or cryptic drug sites in disease-relevant proteins that might be missed using conventional methods of target discovery. PhoreMost has developed a number of partnerships and an exciting pipeline of first-in-class drug discovery programmes spanning multiple therapeutic areas including oncology, immuno-oncology, and ageing. Our technology is positioned to massively expand the diversity of novel therapeutics for several key diseases of unmet clinical need – we are drugging the undruggable. 

PhoreMost® is proud to be an equal opportunities employer. We are committed to creating an inclusive working environment and we celebrate diversity. Every application will be evaluated based on merit and without discrimination. 

Roles and responsibilities: 

  • Responsible for planning, developing and executing a wide range of biochemical assays, including HTRF, FP and other fluorescent based assays for compound profiling 
  • Required to independently develop rational experiments and trouble-shoot when needed
  • Maintain awareness of current developments in literature and contribute pro-actively with ideas to projects and identify opportunities in the workplace for continuous improvements
  • Present results to broader project team members to help influence and drive our drug discovery projects 


  • PhD or equivalent work experience in life sciences with at least three years subsequent research experience in industry 
  • Expert in biochemical assay development and optimization experience within drug discovery environment 
  • Excellent team player, exceptionally driven and actively seeking to learn and develop 
  • Attention to detail, structured thinking, good communication and time management skills 
  • Committed to the pursuit of new therapies for critical unmet clinical need 

 Desired additional requirements (but not required): 

  • Experience in biophysical assays 

Benefits: Equity Participation, Bench-marked Salaries, Life Assurance, Discretionary Bonus, Private health and others 

You must be eligible to work in the UK to apply for this role 


Paddy Shipp | 07469 155 531

William Clarke | 01223 347 294

Howard Group